The 2-Minute Rule for cees dekker

The 2-Minute Rule for cees dekker

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Making use of single-molecule optical and AFM imaging and drive-spectroscopy tactics, we seek out to unravel the mechanistic elements of the composition and dynamics of chromosomes. Our exploration passions contain:

It absolutely was only inside the nineteen nineties even though, when nanotechnology experienced Sophisticated to your level where by single molecules can be manipulated, that the initial experimental equipment began to seem.

Multicolor imaging in the bacterial nucleoid and cell division proteins with blue, orange, and near-infrared fluorescent proteins

2007, initial authentic-time detection of strand Trade in homologous recombination by RecA; discovery of a lower persistence duration of ends of microtubules; and solved the system of biosensing with carbon nanotubes

2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and first at any time study with the dynamics DNA supercoils and the discovery of supercoil hopping

The coiled-coil with the human Rad50 DNA fix protein contains specific segments of greater versatility

We condition micro organism into varieties that deviate from their normal phenotype. Exclusively, I will display our ability to condition Stay E. coli microorganisms into novel shapes such as rectangles, squares, triangles and circles.

2000, discovery that nanotubes can have incredible huge latest densities; resolved the controversial concern of Digital transportation by means of DNA molecules by measurements of insulating habits at The one molecule level; and demonstration of an AFM procedure for single-molecule manipulation of nanotubes

‘Sure, I have an understanding of folks were being stunned at some time. At the end of the nineties, Once i was in my forties, ceesdekker I had been Professor of Molecular Electronics and I have to admit that it experienced become a little bit bored, I didn’t learn Considerably anymore. The field went far more into the applying side, how you might combine nanotubes into electronic circuits.

There was a person issue even though — we did not observe any measurable electrical conduction from The only polymer molecules. We concluded that at The only-molecule degree, conducting polymers have been in fact not these terrific conductors, which was rather disappointing. We thus broadened our see to try to locate much more promising molecules.

An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes

2006, initial demonstration of molecular sorting in the lab with a chip utilizing biomotors; discovery of nanobubbles in reliable-point out nanopores; and first estimate of electrokinetic Vitality conversion inside of a nanofluidic channel

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes

‘I'm pushed by wonder and queries. On a fabric stage I obtain responses in physics, but I encounter my deepest joy with God. That faith also drives my science And the way I take care of persons.